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Cancer Cell 2012;22:631-44

Evidence-based efficacy of glutathione as an oral-lightening agent On review of literature, we could find only two studies that evaluated the efficacy of oral glutathione as a skin-lightening agent

It is not considered likely to cause any undesirable effects during pregnancy

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Depletion of total GSH also directly impacts on E GSH and thus mutants with defects in GSH biosynthesis may cause constitutive activation or inactivation of respective signaling pathways

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