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In the anabolic methionine cycle, niacin, in the form of NAD, is a necessary co-factor for the enzymes dihydrofolate reductase in the folate/tetrahydrobiopterin cycle and S-adenosylhomocysteine hydrolase (1)

A more comprehensive understanding of the pathways and processes of UC will facilitate the development of new therapeutic targets and improve existing treatment methods, with the ultimate goal of improving the quality of life of UC patients

If identified, B12 injections can be part of a treatment plan designed to enhance energy levels and overall quality of life

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Vitamin B12 is essential for myelin production, the protective sheath around nerve fibres that enables efficient nerve signal transmission

10.1038/nprot.2006.116 [DOI] [PMC free article] [PubMed] [Google Scholar] Vukojevi, J