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Physiological factors such as stress influence the wound healing process by affecting blood flow, skin metabolic and immune status, as well as hair follicle function through neurohormonal and steroid hormone levels

This increased demand for oxygen supply causes oxidative stress and, ultimately, muscle damage

ROS generation contributes to the activation of MLKL during necroptosis in lung cancer cells [131] and serves as a downstream event triggered by MLKL upon the induction of necroptosis in colon adenocarcinoma cells [132]

noted an antidepressant-like effect on both wildtype and Huntington-disease murine models, which was noted to be due to decreased mitochondrial oxidative stress [33]

doi: 10.1186/1476-511X-12-6

Am J Physiol Cell Physiol 2003