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Ligand responsive shifts suggest that the deoxyadenosyl moiety in coenzyme B12 has a steric trans influence

Control mice were injected with citrate buffer

J., Meyer-Bahlburg, H

The transition state searches were carried out using B3LYP/6-31 G** for C79, C26, and C83 and B3LYP/6-31 G* + for C23 and C8, as this protocol reliably locates transition states (verified by a single imaginary frequency obtained for each transition state see Supplementary Table 9)

Fish were fed daily by hand at a feeding rate of 1.2-1.5% of total sh body mass in both fish groups following regulation of the temperature and oxygen level

These effects may help some patients eat less and manage their progress more effectively under medical supervision