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doi: 10.1136/ard.62.6.572 [DOI] [PMC free article] [PubMed] [Google Scholar] 222.Milionis HJ, Kakafika AI, Tsouli SG, et al

Figure 2 2.4

Activation of the integrated stress response pathway induces the secretion of GDF15 which serves as a biomarker of mitochondrial dysfunction 37,38,39

102,201 A recent study conducted in the Japanese revealed that even among healthy, lean, normotensive individuals, the presence of hyperuricemia is associated with an elevated risk of cardiometabolic disease
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