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Systemic diabetes is associated with elevated plasma and urinary copper concentrations

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Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Crabtree JS, Wang Y, Roe BA, Weisemann J, Boguski MS, Agarwal SK, Kester MB, Kim YS, Heppner C, Dong Q, Spiegel AM, Burns AL, Marx SJ

The compound discussed here is investigational, and the published research on it is largely preclinical

Lau AW, Liu P, Inuzuka H, Gao D

Nevertheless, until such studies are completed in greater detail and quantity, an early proactive blood pressure control and attentive cardiovascular monitoring are the essential elements for treating patients with VEGF inhibitor induced hypertension