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The rate of choroidal nevi transforming into melanoma is estimated at approximately 1 in 9000 per year

Matveeva et al

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doi: 10.1021/ac070195u

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Consult a medical professional if new caf au lait spots continue to develop, if there are 6 or more caf au lait spots, or if caf au lait spots are accompanied by other skin conditions such as freckles in the armpits or skin growths
