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The protein encoded by the CTLA4 gene is also involved in regulating T cell activation and like polymorphisms in the PTPN22 gene, polymorphisms in CTLA4 are associated with other autoimmune disorders such as Addison disease and Graves disease

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Your body keeps storing excess sugar as fat, and if your diet is carbohydrate-dominant, it becomes difficult for the body to burn fat and more likely to hang on to it

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