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Description
Once in the nucleus, Nrf2 binds to antioxidant response elements (AREs) in the promoter regions of target genes
GHK-Cu helps reverse this process by enhancing gene expression involved in matrix regeneration and suppressing matrix-degrading enzymes like MMPs
doi:10.1158/1055-9965.epi-03-0188
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Br J Clin Pharmacol 2000
The present study further showed that the serial proportion of new bone formation increased gradually over time, with 16%, 27%, 34%, and 40% of our patients at 6 months, 1 year, 2 years, and 3 years, respectively
