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After intravenous injection of autologous bone marrow-derived MSCs, we found the expression of IL-4, IL-10, and TGF-1 was increased by BM-MSCs through the inhibition of Th1 activity, thereby enhancing Treg function ( MCS can directly or indirectly regulates local matrix components through secreting vesicles or exosomes and promotes the repair of damaged joint tissues
[DOI] [PMC free article] [PubMed] [Google Scholar] [25].Jin RC, Mahoney CE, Coleman Anderson L, Ottaviano F, Croce K, Leopold JA, et al

Hepatocyte necrosis and degeneration precede membrane disruption, resulting in the release of hepatic biomarkers into the bloodstream and their subsequent elevation in blood levels 45

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