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In cancer biology and neurodegenerative disease, NNMT-driven SAM depletion alters epigenetic landscapes and gene expression patterns critical for cellular survival

Patients should also be aware that certain medicationssuch as proton pump inhibitors (PPIs) and metformincan interfere with B12 absorption, though this is less relevant once on injection therapy

When evaluating the associations between SBP and hyaluronidase activity, as well as AQP2/creatinine ratio, significant correlations were found only in the NT- group ( Tables 3 , 4 , respectively)

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