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Different supplementation regimes to treat perioperative vitamin B12 deficiencies in bariatric surgery: A systematic review

Methylcobalamin is considered the most bioavailable form and is particularly beneficial for nerve health as it readily penetrates the nervous system

Cost differs between the two forms

Research has documented improvements in metabolic markers including lipid profiles (reduced total cholesterol, LDL, and triglycerides), better insulin sensitivity markers, and reduced inflammatory markers

Both compounds are believed to act through the same general pathway: Lipolysis stimulation They appear to activate beta-3 adrenergic receptors (3-AR), which are found predominantly in adipose (fat) tissue
