palmitoyl-l-carnitine Frontiers Fatty acid oxidation and carnitine

Obayashi K, Kurihara K, Okano Y, Masaki H, Yarosh DB

To further investigate the role of lipid catabolism in fasting-induced longevity, we examined two key regulators: Adipose Triglyceride Lipase-1 (ATGL-1), which initiates lipolysis, and Carnitine Palmitoyl Transferase-2 (CPT-2), which catalyzes carnitine removal and Coenzyme A conjugation to the fatty acid within the mitochondrial matrix 43,44

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide

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The fat is being mobilized