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The unique properties of reducible linkers make them an attractive choice for delivering highly potent drugs, ensuring that the payload is released precisely where it is needed most, thereby maximizing the therapeutic index of ADCs

doi: 10.1016/j.bbamcr.2018.02.010 48 YamamotoMKenslerTWMotohashiH

Interestingly, 7,25-OHC was the only oxysterol to have sustained production over the course of inflammation

These benefits include bypassing the blood-retina barrier for targeted drug delivery, prolonged drug release and reduced systemic side effects

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Histone acetyltransferase (HAT) and histone deacetylase (HDAC) are important for regulating gene expression
