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Zheng X, Wang X, Lan Y, Shi J, Xue SJ, Liu C (2009) Application of response surface methodology to optimize microwave-assisted extraction of silymarin from milk thistle seeds

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It was further noticed that the provision of curcumin (100 mg/kg) greatly reduced the infiltration of macrophages into kidney and the expression of pro-inflammatory cytokines, including TNF- and IL-1 accompanied with the inhibition of NF-B in animals suffering from STZ diabetes (Soetikno et al., 2011)