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4.1 Immune and inflammatory response Chronic inflammation and immune dysregulation are key drivers of CKD progression

(Vienna) 125 , 575589 (2018)

1.2 Advantages of traditional Chinese medicine in multi-target regulation and holistic therapy The progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) constitutes the principal pathological hallmark of PD (11), with oxidative stress recognized as a key driving mechanism

A simplified herbal decoction attenuates myocardial infarction by regulating macrophage metabolic reprogramming and phenotypic differentiation via modulation of the HIF-1/PDK1 axis

[6] Sheng ZG, Tang Y, Liu YX, et al

Parkinson's disease damage to nerve cells in the brain, which contributes to this condition