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10.1007/s00394-014-0704-1 Eur J Nutr
Importantly, iron deposition also correlates with quantitative memory decline
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The formation of DNA single-strand breaks represents a critical aspect of peroxynitrite-mediated cytotoxicity, since they represent the obligatory trigger for the activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) (1243), a pathway ultimately related to the induction of cell death and tissue inflammation, as developed in detail in the next section
