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GSNOR activity is also a major regulator of intracellular GSNO and SNO levels, playing a key role in regulating plant resistance (Liu et al., 2001
Proximity-induced degradation of NSD2 does not perturb FBXO22-dependent BACH1 degradation A potential off-target concern of small molecule degraders is that repurposing the E3 Ub ligase will disrupt the ubiquitination and degradation of its native substrates
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Popa MM, Sirbu AE, Malinici EA, Copaescu C, Fica S
Release 319, 322332
Patel JN, Mueller MK, Guffey WJ, Stegman J
