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Additionally, the In Vitro Studies subsection was updated to note that ganaxolone is a substrate of the UGT enzymes listed above, and that ganaxolone does not inhibit those enzymes

General cell culture and imaging The HeLa cell line used in this study was purchased from American Type Culture Collection (ATCC) and grown in DMEM (Gibco, 11965) media supplemented with 10% FBS and 1% 1003 Pen Strep (Gibco)

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In this context, the peptidase, DJ-1 could have a prominent role because it possess reactive cysteines and is a modulator of mitochondrial dynamics and mitophagy (Thomas et al., 2011)
