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At very high oral doses (54 mg), gastrointestinal side effects increased significantly

These options are usually best suited for people whose deficiency comes from not getting enough B12 in their diet, a common issue for vegans and vegetarians

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Janke R, Dodson AE, Rine J

Frequency (Loading and Maintenance): Regimens vary by country and condition, but representative examples include: Pernicious anemia or severe deficiency: Start with an intensive phase: e.g

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That conceptual shift may be as valuable as the compound itself