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In our previous experiments, the Atgstu19 mutants were characterized by lower vitality, higher H 2 O 2 levels, and less negative redox state in RAM compared to wild type plants under salt stress (Horvth et al

This initiates rapid activation of NF-B and MAPK signaling, resulting in the production of pro-inflammatory cytokines (e.g., TNF-, IL-1, IL-6) and chemokines (e.g., C-X-C Motif Chemokine Ligand 8 (CXCL8), CC Motif Chemokine Ligand 2 (CCL2)), which recruit immune cells to irradiated tissues [65]

Despite its substantial clinical burden, the neural mechanisms underlying heightened anxiety vulnerability in ASD remain poorly understood

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These canonical functions positioned DHODH primarily as a metabolic enzyme critical for nucleotide biosynthesis and cellular proliferation, before its more recent identification as a mitochondria-specific ferroptosis suppressor in select cancer contexts