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It is synthesised primarily in the liver and is the most abundant endogenous (body-produced) antioxidant in human cells, with concentrations highest in hepatic, lung, kidney, and immune tissue

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A larger clinical trial randomly assigned more than 500 patients with type 2 diabetes and symptomatic peripheral neuropathy to one of the following treatments: (i) 600 mg/day of intravenous lipoic acid for three weeks followed by 1,800 mg/day of oral lipoic acid for six months, (ii) 600 mg/day of intravenous lipoic acid for three weeks followed by oral placebo for six months, or (iii) intravenous placebo for three weeks followed by oral placebo for six months (76)

Cell size measurements and mitochondrial mass quantification protocol Live cell size measurements were performed by flow cytometry, using single-cell cytograms to identify and exclude doublets or cell aggregates

This molecular similarity can trigger the autoimmune attack on thyroid tissue that characterises Hashimotos thyroiditis

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