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Both isoforms are found in nearly equal amounts in physiological conditions (MacVicar and Langer, 2016)

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Gharibo says that it depends on the patient and the clinicians judgment as far as which injection should be performed, and which steroid should be injected, and whether a cortisone or steroid should be injected at all. For example, nerve blocks for facet joints and trigger point injections may not involve steroid injections