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The search was limited to articles published in English up to June 2023

Theres yet another serious issue that B12 deficiency causes and thats accumulation of homocysteine and methylmalonic acid in the blood but it doesnt produce any specific symptoms a blood test would be able to reveal these issues (EFSA, 2015
J Alzheimers Dis

If our clinician feels there may be an underlying condition it may be recommended that you have a full consultation with one of our doctors

Plasma concentrations decline significantly with age from ~200 ng/mL at age 20 to ~80 ng/mL by age 60 making it a compelling target for age-related tissue maintenance and periodontal health

Be realistic: Benefits in humans are not proven and research is ongoing
