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Grade I involves ligament stretching with microscopic tears, minimal swelling, and preserved joint stability

10.1096/fj.201801375RR 40 LiangX.HuQ.LiB.McBrideD.BianH.SpagnoliP.et al (2014)

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In some embodiments, the percentage of active agent is varied between about 1% and about 95%, between about 5% and about 80%, between about 10% and about 60% or more of the weight or volume of the total pharmaceutical formulation
