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Theranostic PSMA ligands with optimized backbones for intraoperative multimodal imaging and photodynamic therapy of prostate cancer

The impairment of the negative feedback was hypothesized to be due to the diminished sensitivity of the glucocorticoid receptors (the glucocorticoid resistance theory) secondary to reduced receptor function and expression, shown in large number of experimental, biological and molecular studies (258)

K.et al (2005)

All electrophysiology recordings were performed at ambient temperature

First, the majority of available data are derived from in vitro and animal models, which do not fully capture the complexity, heterogeneity, and long-term progression of human neurodegenerative diseases