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Of the 13 cytokines assayed, epithelial cells secreted detectable amounts of IL-1, IFN-2, MCP-1, IL-6, IL-8, and IL-10, with treatment-dependent modulation observed only in MCP-1, IL-6, and IL-10 (Table 5)

It stems from deeper imbalances like poor gut motility or structural blockages

10.3390/molecules27165324 188 Moreno-VillanuevaM.PfeifferR.SindlingerT.LeakeA.MllerM.KirkwoodT

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Downregulation of intracellular free iron by inhibiting ferritinophagy and ferroptosis may be an effective therapeutic target for CKD

115, pp