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Similarly, triptolide was implicated in the treatment of the breast cancer cell line MCF-7 through the induction of autophagy-mediated cell death by increasing ERK1/2 phosphorylation 43

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The administration of L-Carnitine in a liquid formulation can also be advantageous for patients undergoing dialysis

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By inducing mitochondrial oxidative stress in the RPE through the conditional deletion of the Sod2 gene (which encodes manganese superoxide dismutase, MnSOD), they were able to restore Sod2 expression in the RPE using adeno-associated virus (AAV) vectors