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Kynurenine, a tryptophan metabolite that increases with age, induces muscle atrophy and lipid peroxidation

One of the most commonly used experimental models of IBD is the administration of an enema containing the contact-sensitizing allergen trinitrobenzenesulfonic acid (TNBS) in ethanol resulting in the development of macroscopic, histologic, and biochemical alterations that are well-characterized (Rachmilewitz et al, 1989

Previously, the patient was seen at his oncology clinic for evidence of cancer progression on his current chemotherapy, rituximab and polatuzumab vedotin, due to an increase in the growth of a bulky tumor on the patients back ( Figure 2 ) The patient was urgently started on a new chemotherapy regimen consisting of ifosfamide, carboplatin and etoposide