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Choice D: Decreased serum concentration of IgG is seen in B-cell deficiencies such as X-linked agammaglobulinemia or common variable immunodeficiency

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Mechanistically, SLC7A5 maintains intracellular amino acid levels, and its loss suppresses mTOR signaling

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[DOI] [PubMed] [Google Scholar] 86.Hadar A., Kapitansky O., Ganaiem M., Sragovich S., Lobyntseva A., Giladi E., Yeheskel A., Avitan A., Vatine G.D., Gurwitz D., et al