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While such inhibition causes modest or undetectable increases in H 2 O 2 contents, it triggers a marked perturbation of both the glutathione pool size and redox state (Smith et al., 1984

In Macaca fascicularis mPGES-2, the dimerization remains similar to the canonical assembly and occurs through an insertion of two -helices and two -strands (3443) between 3 and 4 that interacts with those of the other monomer (Figure 5E) (Yamada et al., 2005

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For this reason, verapamil is considered to be the most dangerous of the CCBs, although any of them can cause death in overdose

West Virginia Medical Journal