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Additionally, the interaction between carotenoids and other antioxidants may significantly contribute to their antioxidant activity in vivo

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[DOI] [PubMed] [Google Scholar] 24.Tan D.X., Manchester L.C., Terron M.P., Flores L.J., Reiter R.J

Pharmacokinetic and toxicokinetics data including children-, pregnancy-, geriatric-, and obesity-related data Adult N-Acetylcysteine was given intravenously and as three fast dissolving and one slow-release formulation, on separate occasions, as a single dose of 600 mg to 10 fasting (5 men and 5 women) healthy volunteers
[DOI] [Google Scholar] 767.Landi F., Martone A.M., Salini S., Zazzara B., Calvani R., Marzetti E., Nesci A., Di Giorgio A., Giupponi B., Santoro L., et al

The toxic effects of certain TCMs are closely related to the systemic exposure levels of their components during metabolism