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The pathogenesis of the chronic pain involves BDNF (microglia-derived)-dependent downregulation of neuronal KCC2 transporter leading to a depolarizing shift of Cl reversal potential ( E Cl )
By embracing the power of vitamin C and glutathione together, we can empower ourselves to achieve optimal health and vitality
Increasing ATP availability, reducing reactive oxygen species (ROS) generation by mitochondrial complex I, inhibiting the mitochondrial permeability transition pore, and stimulating mitochondrial biogenesis, all seem to stabilize synaptic functions
Wang, F., Graham, W
Among the theories that explain the aging process, the free radical theory of aging is long-established (Harman, 1956)
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