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Association of primary (1) site and molecular features with progression-free survival (PFS) and overall survival (OS) of metastatic colorectal cancer (mCRC) after anti-epidermal growth factor receptor (EGFR) therapy

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Mitochondrial damage can trigger mitochondrial DNA (mtDNA) release, activating the cGAS-STING1 pathway and potentially contributing to ferroptosis, as observed with inducers like zalcitabine (116)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 217.Aman Y., Schmauck-Medina T., Hansen M., Morimoto R.I., Simon A.K., Bjedov I., Palikaras K., Simonsen A., Johansen T., Tavernarakis N., et al