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Shan et al., 2012

An elevated level of AChE metabolises more acetylcholine and decreases its level in the synapses and then disturbs cholinergic neurotransmission, which results in memory impairment (8)

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This is predicted to be from an upregulation of human growth hormone (HGH)

Over the last decade, the prevalence of high-risk drinking, defined by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) as more than four drinks per day or 14 in a week for men, and more than three drinks a day or seven per week for women as well as AUD, has increased globally