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There are eight types of GPX family in mammals (GPX1, GPX2, GPX3, GPX4, GPX5, GPX6, GPX7, GPX8), of which GPX1-4 and GPX6 of mammals are considered to be selenoproteins containing selenium, which have antioxidant functions, and GPX6 is only expressed in the human body (Brigelius-Floh and Maiorino, 2013

The utilization of available oxygen by mitochondria, which are present only at the periphery, appears to be responsible for maintaining the gradient and the very low oxygen level in the nucleus

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NAD + modulates RNA processing Decorating of RNA as a nucleotide analog Chemical modifications of the RNA 5-end play a pivotal role in various biological functions including the protection of RNA from exonuclease cleavage, the recruitment of proteins for pre-mRNA processing and nuclear export and the initiation of protein synthesis