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44 Additionally, in patients who are already taking some form of oral B 12 supplementation, demonstrating B 12 deficiency can be a challenge, even when symptoms are typical (including those of neuropathy-like paraesthesia and numbness) as serum B 12 concentrations may be just within, or sometimes above, the normal range

Spalding KL, Bernard S, Naslund E, Salehpour M, Possnert G, Appelsved L, Fu KY, Alkass K, Druid H, Thorell A, et al

Vitamin B12 deficiency in over 16s: diagnosis and management.

After 4 weeks, the treatment groups MMSE scores didnt improve more from baseline than did the placebo groups

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Compounded MIC+B12 is not FDA-approved