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Cortisol and aldosterone are low in both LC (neuropathic) and CFS hyperadrenergic POTS (Okamoto et al., 2012)

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Typical ranges from individual peptide research: BPC-157 in rat studies : 10 mcg/kg most common (range: 1-1000 mcg/kg) TB-500 in mouse studies : 10-100 mcg/kg typical range Combination protocols (anecdotal clinical use only): Often 1:1 ratio by mass

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Alterations in cerebrospinal fluid DSIP levels have also been noted in models of depressive behavior, supporting further exploration of its role in mood-related research