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Description
Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder

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Rho0 cells are depleted of mitochondrial (mt) DNA, and thus exhibit functional impairments in Complexes I, III, IV, and V (protein subunits some of which are encoded by mtDNA), resulting in a loss of mitochondrial respiration 18

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