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Topical collagen: Topical treatments called "collagen creams" frequently comprise intact collagen (too large to penetrate skin), hydrolyzed collagen fragments (slightly smaller), and collagen-stimulating chemicals (peptides, retinoids)
As there was not significant toxicity of silymarin reported in human studies, this substance can be used with anti-tuberculosis drugs as a supplement added to the diet (13)

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Furthermore, the combined application of MNPs and PEI resulted in a more pronounced decrease in the viability and IC 50 values of A2780 cells than A2780/CP cells after 48 h