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Administration of tissue plasminogen activator (tPA), which restores blood flow by dissolving blood clots, is considered the gold standard for ischemic stroke and has saved the lives of countless lives and improved patient outcomes

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doi: 10.1046/j.1365-2265.2003.01791.x 39 RajaramSBaylinkDJMohanS

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Burgess S, Mason AM, Grant AJ, Slob EAW, Gkatzionis A, Zuber V, Patel A, Tian H, Liu C, Haynes WG, Hovingh GK, Knudsen LB, Whittaker JC, Gill D (2023) Using genetic association data to guide drug discovery and development: review of methods and applications