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In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)

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How AOD-9604 Works at the Molecular Level AOD-9604 mimics the lipolytic (fat-burning) region of human growth hormone without binding to growth hormone receptors

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Last Updated On 15 Jun
