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Current investigational drugs target pro-oxidant enzymes, lipid peroxidation, and antioxidant mechanisms (Table 7)

In addition, stavudine and didanosine, two drugs that are rarely used as main therapy, sometimes prescribed in combination with highly active antiretroviral therapy, can produce acute life-threatening lactic acidosis

Pharmacol Rev 60:79127 Afshin-Majd S, Bashiri K, Kiasalari Z, Baluchnejadmojarad T, Sedaghat R, Roghani M (2017) Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinsons disease in the rat

It belongs to the group of amino acid derivatives and is formed from the essential amino acids lysine and methionine

& Alemi, S

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