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Patients with fatigue and cognitive disorders may require an increased amount of certain amino acids that cannot be obtained from normal diet alone

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Moreover, in brain of this APPM631L-modified J20 mouse, in contrast to the regular J20 mouse, A42 deposition was not plaquelike but rather punctate in nature, from which we speculate that Met35 of A42 conceivably could be important in oligomer and subsequent plaque formation as well as in oxidative damage associated with this neurotoxic peptide (119)

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SD: standard deviation