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Description
Our previous study (Li et al., 2017) revealed higher expression levels of NNMT in the toe extensor muscle, typically reliant on anaerobic energy metabolism for power generation, compared to the soleus muscle, typically reliant on aerobic energy metabolism
Persistent accumulation of activated myofibroblasts within lesional tissue, the hallmark of SSc and other forms of fibrosis, is induced by transforming growth factor- (TGF-), interleukin-6 (IL-6), and a host of other soluble factors 3,8

Yellow Card report a side effect or safety concern

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A change in NO signaling is not automatically beneficial or harmful

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