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But cyanocobalamin is safer and more widely used

A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss

Reported side effects from clinical practice: Contraindications: Pregnancy, breastfeeding, active cancer, and known hypersensitivity

GLP-1 agonists primarily reduce appetite and slow digestion, leading to reduced calorie intake

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For growth, the main outcome will be measured when the child is 12 months