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B12 shots are safe for most people, but those with certain health conditions should consult a doctor before starting treatment

ICD-10-CM Code D51.0 Definition and Clinical Description The CDC ICD-10-CM web tool defines D51.0 as Vitamin B12 deficiency anemia due to intrinsic factor deficiency. This medical classification captures a specific pathophysiology: autoimmune destruction of gastric parietal cells reduces intrinsic factor production, which prevents B12 binding and absorption in the terminal ileum

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At 34 weeks follow up, it was found that the vitamin capsule neither decreased incidence of CIPN nor pain score significantly compared with placebo