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Found naturally in the body, acetyl-l-carnitine supports the availability of acetyl-CoA, an important energy generating metabolite

He named it vagusstoff ("vagus substance"), noted it to be a structural analog of choline and suspected it to be acetylcholine

Vitamin C, B5, and B6 support the reduction of tiredness and fatigue, while chromium helps maintain balanced metabolic function

Commonly suggested biomedical hypotheses to explain PAIS (such as in long COVID/PASC, ME/CFS) are chronic stimulation of the immune system by a persistent infection or persistent unviable pathogen structures

Funding CS was member of the Radboudumc Center of Expertise for Neuromuscular Disorders (Radboud-NMD), the Netherlands Neuromuscular Center (NL-NMD), and the European Reference Network for rare Neuromuscular Diseases (EURO-NMD)