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Background Vitamin B12 (cobalamin) is essential for normal red blood cell formation, certain enzyme reactions, and neurologic function

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However, the results of these studies have been inconsistent, and the mechanisms behind these associations are still not well understood

Immunohistochemistry of Ki67 used VECTASTAIN-ABC (Vector Laboratories) with 40 objective image capture (Olympus EX51 Microscope)

Furthermore, as mentioned before (see Section 2.1, Isoprenaline-myocardial infarction [38]), we demonstrated that, in addition to the isoprenaline-myocardial infarction [38], the other major noxious events [31,37,38,39,40] also acutely caused the prominent heart failure and widespread dysfunction similar to that observed in rats after the occlusion of the peripheral [19,24,29] and central [27] vessels