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However, a few of his statements might be perceived as nave or overly simplistic and do not align with established medical literature
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Until very recently it was difficult to measure CB1 internalization in presynaptic terminals, but a recent study using super resolution microscopy in hippocampal GABAergic terminals indicated that chronic 9 -THC treatment does indeed produce internalization of CB1 (Dudok et al., 2015)

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To view a copy of this licence, visit About this article Cite this article Krishna, S., Dungan, K.M., Shah, R

These effects are typically short-lived and well tolerated when used as directed